|
KMID : 0370220080520040259
|
|
Yakhak Hoeji
2008 Volume.52 No. 4 p.259 ~ p.263
|
|
|
Inhibition of Nitric Oxide Production by the Extracts of Hibiscus manihot
|
|
Park Eun-Young
Yang Ki-Sook
|
|
|
Abstract
|
|
|
|
Anti-inflammatory activity of the extracts of Hibiscus manihot was investigated through the evaluation of its inhibitory effect on the production of inflammatory biomarkers (i-NOS, COX-2) in RAW264.7 murine macrophage cells. Among the sequential solvent fractions (hexane, dichloromethane, ethyl acetate, n-butanol and water), the fractions of dichloromethane (1 μg/ml) and ethyl acetate (5 μg/ml) showed potential inhibitory activities on i-NOS and COX-2 activity in RAW264.7 cells. These results suggest that Hibiscus manihot might have an anti-inflammatory activity through the suppression of inflammatory markers
|
|
|
KEYWORD
|
|
|
Hibiscus manihot, i-NOS, COX-2, RAW264.7 cells
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|